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VIAGRA is supplied as blue, film-coated, rounded-diamond-shaped tablets containing sildenafil citrate equivalent to 25 mg, 50 mg, or 100 mg of sildenafil. Tablets are debossed with PFIZER on one side and VGR25, VGR50 or VGR100 on the other to indicate the dosage strengths. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. Sildenafil is a phosphodiesterase type 5 (PDE-5) inhibitor. It blocks the action of the enzyme PDE-5, which destroys cyclic guanosine monophosphate (cGMP). An increase in cGMP levels leads to relaxation of the smooth muscles in the penis and increased blood flow, which contributes to an erection.
When your brain sends pyschosexual signals down your spinal cord, this encourages an erection. The penis retains the increased blood within it and stays temporarily stiff. Sildenafil acts on the enzymes responsible for muscle contraction within the blood vessels
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